Evaluation of Biocompatibility of Metallic Implant Materials
Prof. Demircan Canadinç, Koç University
Date: Wednesday, April 2, 2014
Place: EA 409
The nickel-titanium (NiTi) shape memory alloy has been utilized in various medical applications owing to its superior shape memory characteristics. Despite its utility as an implant material for over three decades, the biocompatibility of NiTi is still subject to debate mainly due to possible Ni ion release in chemically aggressive enviroments. The current work was undertaken with the motivation of establishing the geometry and human body location dependencies of the biocompatibility of NiTi alloy while also evaluating the standard biocompatibility experiments from a critical point of view. Specifically, both standard static immersion experiments and a new set of tests were designed to challenge the biocompatibility of NiTi for targeted long-term utility in direct contact with blood, intraoral environment and gastric fluid. Furthermore, another biocompatible material, namely the niobium-zirconium (NbZr) alloy was subjected to mechanical experiments to test its suitability for orthopedic impants, where a multi-scale modeling approach was employed to accurately predict the material’s response under impact loading.
Dr. Demircan Canadinç received his Bachelor of Science in Mechanical Engineering from the Middle East Technical University in 2000. Following his graduation, he moved to United States, where he received his Master of Science and Doctor of Philosophy degrees in Mechanical Engineering from the University of Illiniois at Urbana-Champaign in 2001 and 2005, respectively. He worked as a post-doctorate research associate at the Materials Science Department of the University of Padeborn in Germany between January 2006 and January 2007. Following an additional eight-month period of post-doctorate research at the University of Illinois, Dr. Canadinç joined the Department of Mechanical Engineering at Koç University in September 2007 as a faculty member. Dr. Canadinç’s research in the areas of multi-scale experimental and computational characterization of metallic materials, advanced high-strength steels, shape memory alloys and biomaterials has led to nearly 50 scientific articles published in respected peer-reviewed international journals, and several conference papers and invited presentations. While his work on the utility of metallic materials for the design and improvement of minimally invasive gastrointestinal surgical equipment resulted in 3 patents, he received the Outstanding Young Scientist Award (GEBİP) from the Turkish Academy of Sciences (TÜBA) in 2010 based on his internationally recognized contributions to the advancing of new generation high-manganese steels.