Profiling with Nanoelectromechanical Systems
Nano-electromechanical Systems (NEMS) are extremely sensitive detectors of physical parameters. In recent years, the applications of NEMS in mass sensing has been gaining importance through demonstrations of mass sensitivities at the single atom levels and mass measurements of single protein molecules. These demonstrations show that is possible to perform sample analysis through NEMS mass measurements (NEMS Mass Spectrometry) especially for physiologically important large molecules and biostructures. However the NEMS literature so far have always treated these large molecules as “point-particles”. Considering the miniaturization trend of NEMS and targeted large molecules, this assumption is no more valid.The project will be the first step for the development of a novel, powerful NEMS sensing tool.