Devam Eden Proje

Marie Curie Career Integration Grant
Marie Curie Kariyer Entegrasyon Fonu


Start Date: March 1st, 2014
Expected Completion Date: March 1st, 2018


Nano-electromechanical Systems (NEMS) are extremely sensitive detectors of physical parameters. In recent years, the applications of NEMS in mass sensing has been gaining importance through demonstrations of mass sensitivities at the single atom levels and mass measurements of single protein molecules. These demonstrations show that is possible to perform sample analysis through NEMS mass measurements (NEMS Mass Spectrometry) especially for physiologically important large molecules and biostructures. However the NEMS literature so far have always treated these large molecules as “point-particles”. Considering the miniaturization trend of NEMS and targeted large molecules, this assumption is no more valid.The project will be the first step for the development of a novel, powerful NEMS sensing tool.

Profiling with Nanoelectromechanical Systems


  • M Yuksel, E Orhan, C Yanik, AB Ari, A Demir, MS Hanay (2019). "Nonlinear Nanomechanical Mass Spectrometry at the Single-Nanoparticle Level", Nano Letters, v.19 p.3583-3589, Full Text, DOI:
  • AB Ari, CM Karakan, C Yanık, II Kaya, MS Hanay (2018). "Intermodal Coupling as a Probe for Nanomechanical Modes", Physical Review Applied, v.9(034024), Full Text, DOI:
  • M Kelleci, H Aydogmus, L Aslanbas, SO Erbil, MS Hanay (2018). "Towards Microwave Imaging of Cells", Lab on a Chip, v.18(463), Full Text, DOI: 10.1039/C7LC01251A
  • JE Sader, MS Hanay, AP Neumann, ML Roukes (2018). "Mass Spectrometry Using Nanomechanical Systems: Beyond the Point-Mass Approximation", Nano Letters, v.18 p.1608-1614, Full Text, DOI: 10.1021/acs.nanolett.7b04301
  • MN Esfahani, Y. Kilinc, Y., MC Karakan, E Orhan, MS Hanay, Y Leblebici, BE Alaca (2018). "Piezoresistive Silicon Nanowire Resonators as Embedded Building Blocks in Thick SOI", Journal of Micromechanics and Microengineering, v.28(045006)
  • A Demir and MS Hanay (2018). "Numerical Analysis of Multi-Domain Systems: Coupled Nonlinear PDEs & DAEs with Noise", IEEE Transactions on CAD, v.37(7)
  • T Kouh, MS Hanay, KL Ekinci (2017). "Nanomechanical Motion Transducers for Miniaturized Mechanical Systems", Micromachines, v.8(4) p.108
  • Eric Sage,, Ariel Brenac,, Thomas Alava,, Robert Morel,, Cecilia Dupre,, Selim Hanay,, Michael L. Roukes,, Laurent Duraffourg,, Christophe Masselon,, Sébastien Hentz (2015). "Neutral particle mass spectrometry with nanomechanical systems", Nature Communications, v.6(6482), Full Text
  • Nyffeler, C., Hanay, S., Sacchetto, D., Leblebici, Y. (2015). "Graphene field effect devices operating in differential circuit configuration", Microelectronic Engineering, Full Text, DOI:
  • Hanay, S., Kelber, S.I., O'Connell, C.D., Mulvaney, P., Sader, J.E., Roukes, M.L. (2015). "Inertial Imaging with Nanomechanical Systems", Nature Nanotechnology, Full Text, DOI:
  • Hanay, S., Kelber, S., Naik, A., Chi, D., Hentz, S., Bullard, C., Colinet, E., Duraffourg, L., Roukes, M. (2012). "Single-Protein Nanomechanical Mass Spectrometry in Real Time", Nature Nanotechnology, v.7 p.602, Full Text
  • Naik, A., Hanay, S., Hiebert, W., Feng, X., Roukes, M. (2009). "Towards Single-Molecule Nanomechanical Mass Spectrometry", Nature Nanotechnology, v.4 p.445, Full Text
  • Roukes, M., Hanay, S., Kelber, S., Naik, A.. "Single-Protein Nanomechanical Mass Spectrometry in Real Time (US Patent Application filed on 9 May 2013, CIT-6192-P, 2012)"
  • Roukes, M., Naik, A., Hanay, S.. "Single Molecule Mass Spectrometry Enabled by Nanoelectromechanical Systems (NEMS-MS), US Patent # 8,227,747"